Can be taken during any trimester of pregnancy.
Dose reduction required in renal impairment (eGFR <60 mL/min/1.73 m2 or CrCl ,60 mL/min)
If patient weighs 40kg or less, consider a lower dose of 60mg every 12 hours(i.e.>23-40 kg dose for those aged >1-12 years)
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